Costs and possible benefits of a two-tier infection control management strategy consisting of active screening for multidrug-resistant organisms and tailored control measures.

摘要: Summary Background Multidrug-resistant organisms (MDROs) are an economic burden, and infection control (IC) measures cost- labour-intensive. A two-tier IC management strategy was developed, including active screening, in order to achieve effective use of limited resources. Briefly, high-risk patients were differentiated from other patients, distinguished according type MDRO, implemented accordingly. Aim To evaluate costs benefits this strategy. Methods The study period comprised 2.5 years. All underwent microbiological screening. Gram-negative bacteria (GNB) classified as multidrug-resistant (MDR) extensively drug-resistant (XDR). Expenses consisted for staff, materials, laboratory, increased workload occupational costs. Findings In total, 39,551 screened, accounting 24.5% all admissions. Of screened 7.8% ( N =3,104) MDRO positive; these mainly colonized with vancomycin-resistant enterococci (37.3%), followed by meticillin-resistant Staphylococcus aureus (30.3%) MDR-GNB (28.3%). median length stay (LOS) 10 days (interquartile range 3–20); LOS twice long P Conclusion Although the a screening not trivial, data indicate that approach is cost-effective when prevented transmissions included cost estimate.