The histiocytoid hemangiomas. A unifying concept embracing several previously described entities of skin, soft tissue, large vessels, bone, and heart.

摘要: Abstract The proposal is made that a number of previously described entities skin, soft tissue, large vessels, bone, and heart actually constitute different manifestations the same basic process, characterized by proliferation highly distinctive type cell descriptively identified as “histiocytoid endothelial cell.” in question are angiolymphoid hyperplasia with eosinophilia related cutaneous subcutaneous disorders, atypical vascular hemangioendothelioma endocardial benign angioreticuloma heart. main proliferates all these conditions has features an cell, but also exhibits histochemical ultrastructural characteristics more akin to those histiocyte. These unusual could be expression morphologic abnormality or represent overgrowth specific yet undefined subpopulation cells, such Majno's “contractile Whether this group proliferative diseases reactive neoplastic nature not immediately apparent, although latter seems likely, However, it clear behavior lesions, group, quite indolent even self-limited, contrast aggressive often fatal outcome true angiosarcomas they so closely resemble on microscopic grounds. term hemangioma” suggested for disorders.