Future medical therapy of reflux esophagitis.

摘要: In recent years, many new systemic medications have been developed as potential therapies for the patient with chronic GER and esophagitis. Despite these therapeutic advances, large numbers of patients continue to symptoms or unresolved complications. To some degree, this may relate uncertainties regarding pathogenesis its complications; i.e., is it primarily due acid/pepsin injury primary motility disorders in esophagus. Many are currently being developed, particularly those ability enhance esophageal contractions--the prokinetic drugs. The main discussed, including possible acid suppression therapies, anticholinergic drugs, that might mucosal barrier. addition, more complex questions effectiveness medical versus surgical therapy, use combined discussed.