Immunochemical heterogeneity of parathyroid hormone in plasma.

摘要: ABSTRACT Immunoreactive parathyroid hormone was measured by radioimmunoassay in extracts of glands and tumors plasmas from patients with 1°, 2° or 3° hyperparathyroidism. On serial dilution most showed approximately parallel behavior 2 3 different antisera. However, plasma specimens referred to the same extract as standard frequently greater immunoreactivity antisera (272 273) than a third antiserum (C329). This anomaly more marked hyperparathyroidism secondary renal insufficiency 1° exhibited some adenomas well. Following parathyroidectomy, apparent disappearance rapid when C329 273 both slower These findings suggest that human is im...