Acute renal failure due to hemolytic uremic syndrome in adult patients.

摘要: Hemolytic uremic syndrome is characterized by the simultaneous occurrence of hemolytic anemia, thrombocytopenia, and renal failure. Clinical/pathologic data, along with treatment outcome 8 adult patients HUS, are described. There were 7 females 1 male, age 30.7 ± 12 years; White Black. Three kidney graft recipients, 2 whom receiving cyclosporine; postpartum; case followed an abortion; occurred prodromic infection; was without a causal factor. All presented hematuria 6 oligoanuria. Laboratory data showed anemia schistocytes, LDH values 2584 2291 U/L, platelets 79,000 40,000/mL, creatinine concentrations 5.9 2.5 mg/dL. Renal biopsy thrombotic microangiopathy. Two had predominant glomerular involvement, cortical necrosis, 4 marked arteriolar involvement. In 5 dialytic therapy performed. treated wit...