The Association Between Idiopathic Hemolytic Uremic Syndrome and Infection by Verotoxin-Producing Escherichia coli

摘要: Forty pediatric patients with idiopathic hemolytic uremic syndrome (HUS) were investigated for evidence of infection by Verotoxin-producing Escherichia coli (VTEC). Fecal VTEC (belonging to at least six different O serogroups including O26, O111, O113, O121, O145, and O157) or specifically neutralizable free-fecal Verotoxin (VT) both detected in 24 (60%) but not 40 matched controls. Ten 15 the former developed fourfold greater rises VT-neutralizing antibody titers, as did other who negative fecal VT. A total 30 (75%) had one more criteria. We concluded that a significant association exists between HUS VTEC. The detection VT was most important procedure early diagnosis this because, our study, never isolated absence VT, whereas often present even when undetectable.