Probabilistic intake assessment and body burden estimation of dioxin-like substances in background conditions and during a short food contamination episode.

摘要: The objective was to perform a dioxin body burden estimate based on probabilistic intake assessment of PCDDs, PCDFs and dioxin-like PCBs because the so-called 1999 'Belgian incident'. Monte Carlo simulation techniques were used combine detailed 7-day food data individual level from sample 14-18-year-old adolescents with 'background' 'incident-related' contamination data. In background conditions, 3% had an <1 pg TEQ kg(-1) bw day(-1), while 85% <4 day(-1). Milk other dairy products basic source contaminants, fish constituted main at higher percentiles intake. During incident, estimated median showed moderate increase. At 99th percentile, highest level, 95% upper bound uncertainty peak burden-23.73 ng bw-remained below burdens that in experimental animal or man are accompanied by population-based observable increase incidence adverse effects. Belgian incident most likely did not affect public health Belgium measurable way, although exceptions remain possible level.