Stability of serum prostate-specific antigen determination across laboratory, assay, and storage time
作者： Steven J. Jacobsen , George G. Klee , Hans Lilja , George L. Wright , Joseph E. Oesterling
DOI: 10.1016/S0090-4295(99)80014-4
关键词:
摘要: Abstract Objectives To understand the comparability of serum prostate-specific antigen (PSA) determinations across assays and storage time. Methods Serum PSA levels were determined for men aged 40 to 79 years from clinical subset Olmsted County Study Urinary Symptoms Health Status Among Men on fresh samples after a median 32 months banked samples, frozen at −70 °C. Baseline by Tandem-R assay. Follow-up IMx assay repeat in different laboratory an immunofluorometric another site. Results The level baseline was 1.0 ng/mL (25th percentile, 0.6; 75th 1.7). distributions determination made follow-up Tandem-R, IMx, analyses essentially identical. Overall, highly correlated. correlations between repeated 0.96, 0.97, respectively (all P Conclusions These data provide important reassurance about use obtained assays, laboratories, properly tored
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