Recommendations for Individual Participant Data Meta-Analyses on Work Stressors and Health Outcomes: Comments on IPD-Work Consortium Papers

摘要: The IPD-Work (individual-participant data meta-analysis of working populations) Consortium has published several papers on job strain (the combination low control and high demands) based Karasek's demand-control model (1) health-related outcomes including cardiovascular disease (CVD), cancer, obesity, diabetes as well behaviors, utilizing meta-analyses a pooled database study participants from 17 European cohorts. An IPD approach some advantages over typical meta-analyses, eg, having access to all the for each individual allows additional analyses, compared meta-analyses. However, such an approach, like other is not free errors biases (2-6) when it conducted appropriately. In our review Consortium's (hereafter called Consortium) publications last two years, we have identified pointed out conceptual methodological errors, unsubstantiated conclusions inappropriate recommendations worksite public health policies (6-15). yet appropriately addressed many issues raised. Also major underlying been presented in comprehensive way, nor they discussed widely among work stress researchers. We are concerned that same could be repeated future by researchers who interested stressors outcomes. It possible interpretations publications, which remained uncorrected date, may negative impact international efforts research community improve populations. Recently, Dr. Tores Theorell, principal investigator Consortium, responded this journal (16) criticisms (17, 18). purpose article discuss substantive remain resolved how analyses. provide or Finally, alternative recommendations, perspective intervention studies.