Isolation and preservation of fetal and neonatal hematopoietic stem and progenitor cells of the blood and methods of therapeutic use
作者： Hal E. Broxmeyer , Edward A. Boyse , Gordon W. Douglas
DOI:
关键词:
摘要: The present invention relates to hematopoietic stem and progenitor cells of neonatal or fetal blood that are cryopreserved, the therapeutic uses such upon thawing. In particular, use for (or immune) reconstitution. Hematopoietic reconstitution with can be valuable in treatment prevention various diseases disorders as anemias, malignancies, autoimmune disorders, immune dysfunctions deficiencies. another embodiment, which contain a heterologous gene sequence used therapy. preferred embodiment he invention, have been cryopreserved thawed utologous (self)
google.co.in 参考文章(13)
Curt I. Civin, Human stem cells ,(1984)
R Schwartz, Method and apparatus for the preservation of cells and tissues ,(1970)
Brian A. Naughton, Gail K. Naughton, Process for replicating bone marrow in vitro ,(1986)
Gerald P. Hirsch, Selim M. Senkan, Method of freezing living cells and tissues with improved subsequent survival ,(1978)
Matti Antero Juhani Junnila, Cryoprotectant solution and method ,(1988)
George Dayian, Arthur W. Rowe, Process for freezing blood platelets ,(1976)
Arthur P Rinfret, Clement W Cowley, William J Timson, Apparatus for the preservation of biological substances ,(1966)
Fabian J. Lionetti, Stephen M. Hunt, Method of isolating and cryopreserving human white cells from whole blood ,(1975)
Dimitri Adamopoulos, John Phillips, Dimitri Viza, Production of specific immune nucleic acids cell dialysates and antibodies ,(1977)
Brian A. Naughton, Gail K. Naughton, Process for replicating bone marrow in vitro and using the same ,(1987)