Rapid Enantiomeric Excess and Concentration Determination Using Simple Racemic Metal Complexes
作者： Sonia Nieto , Vincent M. Lynch , Eric V. Anslyn , Hyunwoo Kim , Jik Chin
DOI: 10.1021/OL802085J
关键词:
摘要: Racemic-metal complexes were used to determine identity, enantiomeric excess, and concentration of chiral diamines using metal-to-ligand charge transfer bands in circular dichroism spectroscopy. It takes under just 2 min per sample [G]t %R with tolerable errors (19% 4%, respectively). The simplicity the achiral receptors employed confers this technique great potential for high-throughput screening.
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