Elevated Levels of Hypoxanthine in Vitreous Humor Indicate Prolonged Cerebral Hypoxia in Victims of Sudden Infant Death Syndrome

摘要: Hypoxanthine levels in vitreous humor from 32 infants who died of sudden infant death syndrome (SIDS) were determined and compared with found eight children trauma, drowning, or hanging seven neonates dying suddenly without long-standing antemortem hypoxia. Determination hypoxanthine level was done either a PO2 electrode method high-performance liquid chromatography. The results obtained by both methods significantly correlated; therefore they pooled. median victims SIDS (380 mumol/L) higher (P less than .001) the violently (118 mumol/L). Moreover, those hypoxia (53 It is concluded that probably not event but may be preceded relatively long period respiratory failure