Development of a core set of domains for data collection in cohorts of patients with ankylosing spondylitis receiving anti-tumor necrosis factor-alpha therapy.

摘要: Objective To create a core set of measurement concepts for use in the creation and maintenance anti-tumor necrosis factor-α patient registries ankylosing spondylitis (AS). Methods A Delphi-based approach was used to identify elements that best patient’s clinical state, disease progression, potential drug-related toxicities. Decision-making based on systematic literature reviews experience expertise. Results domains defined including activity physical function outcomes. Comparison with existing AS showed excellent agreement current practice. Conclusion This is basis data collection across populations.