摘要: Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disease which causes pain along with loss of physical function and quality life over many years. It has also been shown to increase mortality compared the general population, independent treatment modalities. Cardiovascular deaths are increased, recent studies suggest both an abnormality lipid regulation microvascular changes. Increased rates suicide, accidental death, alcohol-related have reported. This review examines increased in AS highlights need focus on cardiovascular risk factors psychological health addition disability patients AS.