Hydration may reverse most symptoms of lower extremity intermittent claudication or rest pain.

摘要: Abstract Background Medical treatment of severe intermittent claudication or critical limb-threatening ischemia causing rest pain frequently achieves only partial relief is not effective at all. Methods Patients with the lower extremities who did improve after control risk factors, supervised exercises, and cilostazol medication were included in this study. All patients treated hydration. They asked to drink 2500 mL fluids (water, soup, milk) during a 24-hour period ingest 0.6 g/kg albumin day, as egg white powder. Total salt administered daily was 3.5 g. Symptoms, skin temperature, ankle-brachial index, concentration serum, time distance recorded before treatment, 6 weeks, 6 months. Electrolytes measured monthly. No additional used Walking encouraged but supervised. The trial has continued indefinitely. For statistical analysis, SPSS software (IBM Corp, Armonk, NY) used. Ethical Committee approved protocol, an informed consent signed by all patients. Results There 132 (94 male, 38 female) Median age 72.5 years (range, 67-77 years); had mean 100 meters pain. Symptoms been present for >5 months patients; 22 (16.8%) Proper hydration, determined drinking least 2000 mL water 24 hours 6 months, achieved 131 compliant Only one patient failed more. Ankle-brachial index improved from 0.6 0.75 (P  Conclusions This study suggests that proper hydration ≥2000 mL complement orally reach 4 g/dL serum could be armamentarium physicians treating disabling caused peripheral artery disease. Further comparative studies assess benefit increasing oncotic pressure are warranted.