作者: Rebecca K. Tsevat , Carmen Radecki Breitkopf , Sara E. Landers , Ariel M. de Roche , Christine Mauro
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摘要: Little is known about how adolescents' and parents' thoughts participation in clinical trials change over time. In this study, adolescent (14-17 years)-parent dyads were asked willingness to participate a hypothetical reproductive health study. A year later, they their the study had changed. Qualitative responses coded analyzed using framework analysis. Thirty-two percent of adolescents 18% parents reported changes thoughts; reasons included general perception, clearer understanding, new knowledge or experiences, increased maturity/age adolescents, participants independent Adolescents may benefit from learning studies multiple times, investigators should account for development experiences optimize research enrollment.