Supresión de la angiogénesis tumoral a través de anticuerpos monoclonales

作者: Adrián Daniel Góngora

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摘要: La angiogenesis es el mecanismo por cual se generan nuevos vasos sanguineos a partir de los pre-existentes. En adultos, la un evento raro excepto durante reparacion heridas o en procesos asociados con ciclo menstrual. Sin embargo, existen desordenes patologicos dependientes angiogenesis, como [...]

参考文章(213)
Jane S. Wey, Fan Fan, Michael J. Gray, Todd W. Bauer, Marya F. McCarty, Ray Somcio, Wenbiao Liu, Douglas B. Evans, Yan Wu, Daniel J. Hicklin, Lee M. Ellis, Vascular endothelial growth factor receptor-1 promotes migration and invasion in pancreatic carcinoma cell lines Cancer. ,vol. 104, pp. 427- 438 ,(2005) , 10.1002/CNCR.21145
Fairooz Kabbinavar, Herbert I. Hurwitz, Louis Fehrenbacher, Neal J. Meropol, William F. Novotny, Grazyna Lieberman, Susan Griffing, Emily Bergsland, Phase II, Randomized Trial Comparing Bevacizumab Plus Fluorouracil (FU)/Leucovorin (LV) With FU/LV Alone in Patients With Metastatic Colorectal Cancer Journal of Clinical Oncology. ,vol. 21, pp. 60- 65 ,(2003) , 10.1200/JCO.2003.10.066
Zhigang He, Marc Tessier-Lavigne, Neuropilin Is a Receptor for the Axonal Chemorepellent Semaphorin III Cell. ,vol. 90, pp. 739- 751 ,(1997) , 10.1016/S0092-8674(00)80534-6
Shuji Yoshino, Mikio Kato, Koichi Okada, PROGNOSTIC SIGNIFICANCE OF MICROVESSEL COUNT IN LOW STAGE RENAL CELL CARCINOMA International Journal of Urology. ,vol. 2, pp. 156- 160 ,(1995) , 10.1111/J.1442-2042.1995.TB00445.X
Ming Zhou, Roy L. Sutliff, Richard J. Paul, John N. Lorenz, James B. Hoying, Christian C. Haudenschild, Moying Yin, J. Douglas Coffin, Ling Kong, Evangelia G. Kranias, Wusheng Luo, Gregory P. Boivin, John J. Duffy, Sharon A. Pawlowski, Thomas Doetschman, Fibroblast growth factor 2 control of vascular tone. Nature Medicine. ,vol. 4, pp. 201- 207 ,(1998) , 10.1038/NM0298-201
Harold F. Dvorak, Michael Detmar, Kevin P. Claffey, Janice A. Nagy, Livingston van de Water, Donald R. Senger, Vascular Permeability Factor/Vascular Endothelial Growth Factor: An Important Mediator of Angiogenesis in Malignancy and Inflammation International Archives of Allergy and Immunology. ,vol. 107, pp. 233- 235 ,(1995) , 10.1159/000236988
Sonja Loges, Massimiliano Mazzone, Philipp Hohensinner, Peter Carmeliet, Silencing or fueling metastasis with VEGF inhibitors: antiangiogenesis revisited. Cancer Cell. ,vol. 15, pp. 167- 170 ,(2009) , 10.1016/J.CCR.2009.02.007
Maria Bastaki, Enrico Emanuele Nelli, Patrizia Dell’Era, Marco Rusnati, Maria Pia Molinari-Tosatti, Silvia Parolini, Robert Auerbach, Luigi P. Ruco, Laura Possati, Marco Presta, Basic Fibroblast Growth Factor–Induced Angiogenic Phenotype in Mouse Endothelium: A Study of Aortic and Microvascular Endothelial Cell Lines Arteriosclerosis, Thrombosis, and Vascular Biology. ,vol. 17, pp. 454- 464 ,(1997) , 10.1161/01.ATV.17.3.454
P. Netzer, M. Domek, R. Pai, F. Halter, A. Tarnawski, Inhibition of human colon cancer cell growth by antisense oligodeoxynucleotides targeted at basic fibroblast growth factor Alimentary Pharmacology & Therapeutics. ,vol. 15, pp. 1673- 1679 ,(2001) , 10.1046/J.1365-2036.2001.01084.X
Kevin P. Claffey, Shu-Ching Shih, Andrew Mullen, Suzan Dziennis, Jennifer L. Cusick, Kristin R. Abrams, Sam W. Lee, Michael Detmar, Identification of a Human VPF/VEGF 3′ Untranslated Region Mediating Hypoxia-induced mRNA Stability Molecular Biology of the Cell. ,vol. 9, pp. 469- 481 ,(1998) , 10.1091/MBC.9.2.469