Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype

作者: Haiquan Lu , Debangshu Samanta , Lisha Xiang , Huimin Zhang , Hongxia Hu

DOI: 10.1073/PNAS.1513433112

关键词:

摘要: … To test this hypothesis, we analyzed MDA-MB-231 subclones that were stably … of the SLC7A11 and GCLM genes is regulated by HIF-1, but not HIF-2. We also implanted MDA-MB-231 …

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