Causes of incidental neutropenia in adulthood

作者: Carmen SP Lima , Erich V Paula , Tatiana Takahashi , Sara TO Saad , Irene Lorand-Metze

DOI: 10.1007/S00277-006-0150-0

关键词:

摘要: The incidental discovery of neutropenia during routine blood counting represents a common problem for clinicians. However, there are no reported data systematic evaluations adults with neutropenia. As such, this was the aim present study. Ninety-seven were submitted to clinical and laboratory approach including medical evaluation, complete count (CBC), serial CBC, direct indirect antiglobulin test, bone marrow smear biopsy, assessment folate, vitamin B12 iron status, serum liver enzymes, proteins, serological exams hepatitis B C virus, cytomegalovirus, mononucleosis, human immunodeficiency virus toxoplasmosis, detection lupus erythematosus cells, antinuclear anti-DNA antibodies rheumatoid factor, dosage free thyroxin thyrotropin, chest roentgenogram abdominal echography. Chronic idiopathic identified in 34.0% individuals, due exposure chemical agents seen 16.5%, infectious diseases 9.3%, autoimmune haematological thyroid disorders 8.2%, ethnic 7.2%, drug-related 2.1%, cyclic 2.1% deficiency 2.1%. Recovery or improvement neutrophil upon treatment recuperation from infectious, autoimmune, supplementation. We conclude that evaluation individuals using structured may make identification clinically silent possible, provide an opportunity early treatment, avoiding complications consequences

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