Proteomics Approach to Identify Biomarkers in Neurodegenerative Diseases.

作者: Annapurna Nayak , Gregory Salt , Sunil K Verma , Uday Kishore , None

DOI: 10.1016/BS.IRN.2015.05.003

关键词:

摘要: This chapter examines the use of proteomics in understanding pathogenesis and identifying possible biomarkers a range neurodegenerative diseases such as Alzheimer's disease, Parkinson's amyotrophic lateral sclerosis, Huntington's prion diseases. We have attempted to look at neuroproteomic approach from biomarker discovery point view. Novel can pave way for new therapeutic targets lead us better involved

参考文章(101)
Rukhsana Sultana, Debra Boyd-Kimball, Jain Cai, William M. Pierce, Jon B. Klein, Michael Merchant, D. Allan Butterfield, Proteomics analysis of the Alzheimer's disease hippocampal proteome. Journal of Alzheimer's Disease. ,vol. 11, pp. 153- 164 ,(2007) , 10.3233/JAD-2007-11203
D A Newsome, F Wolford, A T Hewitt, N C Leone, E D Miller, M Swartz, Macular degeneration and elevated serum ceruloplasmin. Investigative Ophthalmology & Visual Science. ,vol. 27, pp. 1675- 1680 ,(1986)
Fadi Abdi, Joseph F. Quinn, Joseph Jankovic, Martin McIntosh, James B. Leverenz, Elaine Peskind, Randy Nixon, John Nutt, Katherine Chung, Cyrus Zabetian, Ali Samii, Melanie Lin, Stephen Hattan, Catherine Pan, Yan Wang, Jinghua Jin, David Zhu, G. Jane Li, Yan Liu, Dana Waichunas, Thomas J. Montine, Jing Zhang, Detection of biomarkers with a multiplex quantitative proteomic platform in cerebrospinal fluid of patients with neurodegenerative disorders Journal of Alzheimer's Disease. ,vol. 9, pp. 293- 348 ,(2006) , 10.3233/JAD-2006-9309
W Krecedilla˜ żel, N Ghyselinck, TA Samad, V Dupé, P Kastner, E Borrelli, P Chambon, None, Impaired Locomotion and Dopamine Signaling in Retinoid Receptor Mutant Mice Science. ,vol. 279, pp. 863- 867 ,(1998) , 10.1126/SCIENCE.279.5352.863
Maria Grazia Spillantini, Marie Luise Schmidt, Virginia M.-Y. Lee, John Q. Trojanowski, Ross Jakes, Michel Goedert, α-Synuclein in Lewy bodies Nature. ,vol. 388, pp. 839- 840 ,(1997) , 10.1038/42166
Natalie Ostrerova, Leonard Petrucelli, Matthew Farrer, Nitinkumar Mehta, Peter Choi, John Hardy, Benjamin Wolozin, α-Synuclein Shares Physical and Functional Homology with 14-3-3 Proteins The Journal of Neuroscience. ,vol. 19, pp. 5782- 5791 ,(1999) , 10.1523/JNEUROSCI.19-14-05782.1999
K. Houi, T. Kobayashi, S. Kato, S. Mochio, K. Inoue, Increased plasma TGF‐β1 in patients with amyotrophic lateral sclerosis Acta Neurologica Scandinavica. ,vol. 106, pp. 299- 301 ,(2002) , 10.1034/J.1600-0404.2002.01301.X
Jeban Ganesalingam, Jiyan An, Christopher E. Shaw, Gerry Shaw, David Lacomis, Robert Bowser, Combination of neurofilament heavy chain and complement C3 as CSF biomarkers for ALS Journal of Neurochemistry. ,vol. 117, pp. 528- 537 ,(2011) , 10.1111/J.1471-4159.2011.07224.X
Thomas Gasser, Genetics of Parkinson's disease. Current Opinion in Neurology. ,vol. 18, pp. 363- 369 ,(2005) , 10.1097/01.WCO.0000170951.08924.3D
D. Allan Butterfield, Isabella Dalle-Donne, Redox proteomics: from protein modifications to cellular dysfunction and disease Mass Spectrometry Reviews. ,vol. 33, pp. 1- 6 ,(2006) , 10.1002/MAS.21404