作者: Roger Stupp , Krisztian Homicsko , J. Gregory Cairncross
DOI: 10.1007/978-1-4614-8363-2_19
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摘要: Malignant gliomas are diffusely infiltrating and thus any local treatment has its inherent limitations. Alkylating agent chemotherapy repeatedly demonstrated improvement in disease-free overall survival. Concomitant chemoradiotherapy with temozolomide is the standard of care glioblastoma, neoadjuvant or adjuvant PCV improves survival anaplastic oligodendroglial tumors a 1p/19q co-deletion, however benefit only seen long follow-up > 6 years. Randomized trials glioma have shown that sequence, radiotherapy first at recurrence reverse, does not matter terms progression-free