Cytokines with possible clinical utility.

摘要: Biological response modifiers (BRM) are agents aimed at reducing tumor growth, not primarily by exerting direct cytotoxic effects but modulation of gene expression (e.g., induction differentiation) or enhancing host defense mechanisms directed against cancer cells. BRM as primary therapy adjuncts to in the treatment cancers have attracted increasing interest view stagnating clinical results many areas [1], and there is evidence vitro vivo efficacy these agents. Furthermore, advances molecular biology suggesting that oncogenes their products play a crucial role oncogenesis support approaches regulatory means controlling cell growth.