PSYCHIATRIC SYMPTOMS | Interictal Anxiety in Temporal Lobe Epilepsy

作者: L.E. Kalynchuk , N.M. Fournier

DOI: 10.1016/B978-012373961-2.00255-1

关键词:

摘要: Psychiatric comorbidities are common in temporal lobe epilepsy (TLE). This article will focus on interictal anxiety, which is a problem for large proportion of patients with TLE and difficult to control. We briefly review important findings from preclinical clinical research this topic. then our own research, the kindling model used studying changes anxiety behavior rats. Finally, we discuss implications these developing better treatment options patient populations offer some thoughts future directions research.

参考文章(15)
Robert E. Adannec, Partial kindling and behavioral pathologies. International Review of Neurobiology. ,vol. 45, pp. 409- 434 ,(2001) , 10.1016/S0074-7742(01)45021-5
Lisa E. Kalynchuk, John P.J. Pinel, Dallas Treit, Tod E. Kippin, Changes in emotional behavior produced by long-term amygdala kindling in rats Biological Psychiatry. ,vol. 41, pp. 438- 451 ,(1997) , 10.1016/S0006-3223(96)00067-4
Amanda J. Wintink, Nicole A. Young, Alicia C. Davis, Andrea Gregus, Lisa E. Kalynchuk, Kindling-induced emotional behavior in male and female rats. Behavioral Neuroscience. ,vol. 117, pp. 632- 640 ,(2003) , 10.1037/0735-7044.117.3.632
Lisa E Kalynchuk, Alicia C Davis, Andrea Gregus, Jason Taggart, C Chris Dodd, Amanda J Wintink, Elliott G Marchant, Hippocampal involvement in the expression of kindling-induced fear in rats. Neuroscience & Biobehavioral Reviews. ,vol. 25, pp. 687- 696 ,(2001) , 10.1016/S0149-7634(01)00051-3
Jeffrey B. Rosen, Jay Schulkin, From normal fear to pathological anxiety Psychological Review. ,vol. 105, pp. 325- 350 ,(1998) , 10.1037/0033-295X.105.2.325
S.J Barnes, J.P.J Pinel, Conditioned effects of kindling. Neuroscience & Biobehavioral Reviews. ,vol. 25, pp. 745- 751 ,(2001) , 10.1016/S0149-7634(01)00054-9
J. Pinel, D Treit, L. Rovner, Temporal lobe aggression in rats Science. ,vol. 197, pp. 1088- 1089 ,(1977) , 10.1126/SCIENCE.560719
V. Helfer, C. Deransart, C. Marescaux, A. Depaulis, Amygdala kindling in the rat: anxiogenic-like consequences Neuroscience. ,vol. 73, pp. 971- 978 ,(1996) , 10.1016/0306-4522(96)00081-4
Lisa E. Kalynchuk, Dallas Treit, John P. J. Pinel, Characterization of the defensive nature of kindling-induced emotionality. Behavioral Neuroscience. ,vol. 113, pp. 766- 775 ,(1999) , 10.1037//0735-7044.113.4.766
A. Depaulis, V. Helfer, C. Deransart, Ch. Marescaux, Anxiogenic-like consequences in animal models of complex partial seizures Neuroscience & Biobehavioral Reviews. ,vol. 21, pp. 767- 774 ,(1997) , 10.1016/S0149-7634(96)00060-7