Changes in emotional behavior produced by long-term amygdala kindling in rats

作者: Lisa E. Kalynchuk , John P.J. Pinel , Dallas Treit , Tod E. Kippin

DOI: 10.1016/S0006-3223(96)00067-4

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摘要: The effects of long-term amygdala kindling on emotional behavior were investigated. In Experiment 1, rats received 99 basolateral amygdala, central or sham stimulations. in both kindled groups displayed more resistance to capture from an open field and open-arm activity elevated plus maze than did the control rats. 2, either 20, 60, 100 stimulations Compared controls, explored less during first 30s a novel field, avoided area resisted being captured engaged maze. magnitude these was greatest 100-stim least 20-stim Together, results suggest that is useful model for studying emotionality associated with temporal lobe epilepsy.

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