Clinical significance of lymph node metastasis in gastric cancer.

摘要: Gastric cancer, one of the most common malignancies in world, frequently reveals lymph node, peritoneum, and liver metastases. Most gastric cancer patients present with node metastasis when they were initially diagnosed or underwent surgical resection, which results poor prognosis. Both depth tumor invasion involvement are considered as important prognostic predictors cancer. Although extended lymphadenectomy was not a survival benefit procedure reported to be associated high mortality morbidity two randomized controlled European trials, it showed significant superiority terms lower locoregional recurrence disease related deaths compared limited 15-year follow-up study. Almost all clinical investigators have reached consensus that predictive efficiency number metastatic nodes is far better than extent for prognosis worldwide, but other nodal classifications been proposed alternatives improving patient It still controversial over whether ratio between examined superior evaluation Besides, negative count has increasingly recognized an factor significantly