Thymocyte subpopulations in young and adult mice

摘要: Abstract In an attempt to correlate morphological aspects of thymic lymphocytes with functional criteria, thymocytes from normal and steroid-treated mice were studied. Electron microscopy was performed on the whole cell suspension or after separation a density gradient. Steroid sensitivity phytomitogen responses different subpopulations compared aspect. Steroid-resistant (Sr) steroid-sensitive (Ss) populations shown be heterogeneous basis their structure density. Sr cells are highly sensitive in all fractions. The three types, which may represent steps maturational procedure, present Ss populations, but proportions. These results additional argument for hypothesis that two pools types cells, following developmental pathways.