Complement resistance-related traits among Escherichia coli isolates from apparently healthy birds and birds with colibacillosis.

摘要: In this study, 294 Escherichia coli isolates from birds with colibacillosis were collected disease outbreaks throughout the United States and compared 75 fecal E. of apparently healthy chickens by their possession several purported virulence genes, resistance to rough-lipopolysaccharide-specific bacteriophages (rLPSr), elaboration capsule. Traits selected for study on basis association complement resistance. The genes targeted in included those encoding colicin V (cvaC) outer membrane proteins TraT (traT), OmpA (ompA), Iss (iss). No significant differences found between two groups occurrence cvaC-, traT-, or ompA-homologous sequences rLPSr. Only a few encapsulated, significantly more likely be encapsulated than sick birds. However, iss, whether detected through hybridization amplification, was disease-associated This difference highly significant. Further, iss widely distributed among different serotypes various avian host species sites within these hosts. Such results suggest that sequence an isolate may good indicator isolate's potential cause disease. warrants further because protein it encodes useful targets future control efforts.