作者: Joseph Schoepfer , Paul William Manley , Robert Martin Grotzfeld , Pascal Furet , Xavier Francois Andre Pelle
DOI:
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摘要: The present invention relates to compounds of formula (I): in which Y, R, R 2, 3 and 4 are defined the Summary Invention; capable inhibiting activity BCR-ABL1 mutants thereof. further provides a process for preparation invention, pharmaceutical preparations comprising such methods using treatment cancers.