Chapter 15 - Peripheral neuropathies

摘要: Peripheral neuropathies are diseases of the peripheral nervous system that can be divided into mononeuropathies, multifocal neuropathies, and polyneuropathies. Symptoms usually include numbness paresthesia. These symptoms often accompanied by weakness painful. Polyneuropathies axonal demyelinating forms, which is important for diagnostic reasons. Most develop over months or years, but some rapidly progressive. Some patients only suffer from mild, unilateral, slowly progressive tingling in fingers due to median nerve compression wrist (carpal tunnel syndrome), while other tetraplegic, with respiratory insufficiency within 1–2 days Guillain–Barre syndrome. Carpal syndrome, a prevalence 5% incidence per 1000 person-years, most common mononeuropathy. Population-based data chronic polyneuropathy relatively scarce. Prevalence estimated at 1% increases 7% persons 65 years age. Incidence approximately 1 person-years. Immune-mediated polyneuropathies like syndrome inflammatory polyradiculoneuropathy rare diseases, an annual 0.2–0.5 100 000 respectively. more prevalent older adults men, except carpal women. Diabetes cause neuropathy associated both mono- Among group polyneuropathies, about 20–25% no direct found.