Comparison of methylene blue-directed biopsies and four-quadrant biopsies in the detection of high-grade intraepithelial neoplasia and early cancer in Barrett's oesophagus
作者： L. Gossner , O. Pech , A. May , M. Vieth , M. Stolte
DOI: 10.1016/J.DLD.2006.05.025
关键词:
摘要: Background. Barrett’s oesophagus embodies the risk of malignant transformation. High-grade intraepithelial neoplasia and early cancer in are often discrete or macroscopically occult lesions show a patchy distribution therefore, directed biopsies combination with four-quadrant random gold standard for surveillance. Aims. The aim this prospective study was to compare methylene blue staining patients neoplasia. Patients methods. Eighty-six (mean age 65 ± 8 years) histologically proven but evident high-grade (n = 17) 69) on HR-endoscopy all together 98 lesions, were included. In first step, taken during routine endoscopy (group I). second performed 0.5% solution spray catheter. Biopsies focal areas decreased stain, heterogeneity stain absence II). Results. 75/86 patients, could be diagnosed group while 56 determined (P 0.053). significantly more blue-directed (80.9% versus 26.4%, P < 0.005) also identified (96/98; 98%) only 58/98 (59%) localised 0.05). When used (1217 562, 0.0001), average number specimens per patient about half that biopsy (6.5 14.1, 0.0001). Conclusions. Chromoendoscopy compared biopsies. addition, less needed use appears improve detection oesophagus. © 2006 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.
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sci-hub.se 参考文章(29)
K. Ragunath, N. Krasner, V. Raman, M. Haqqani, W. Cheung, A Randomized, Prospective Cross-Over Trial Comparing Methylene Blue-Directed Biopsy and Conventional Random Biopsy for Detecting Intestinal Metaplasia and Dysplasia in Barrett’s Esophagus Endoscopy. ,vol. 35, pp. 998- 1003 ,(2003) , 10.1055/S-2003-44599
Richard E. Sampliner, , Practice guidelines on the diagnosis, surveillance, and therapy of Barrett's esophagus. The Practice Parameters Committee of the American College of Gastroenterology. The American Journal of Gastroenterology. ,vol. 93, pp. 1028- 1032 ,(1998) , 10.1111/J.1572-0241.1998.00362.X
L. H. Sobin, 英伸 渡辺, 邦夫 太田, Jeremy R. Jass, Histological typing of oesophageal and gastric tumours ,(1990)
Wolfram Siede, Graham C. Walker, Errol C. Friedberg, DNA Repair and Mutagenesis ,(2006)
Suzy L Kim, J.Patrick Waring, Stuart Jon Spechler, Richard E Sampliner, Wilhelm G Doos, William F Krol, William O Williford, Diagnostic inconsistencies in Barrett's esophagus Gastroenterology. ,vol. 107, pp. 945- 949 ,(1994) , 10.1016/0016-5085(94)90217-8
Douglas S. Levine, Rodger C. Haggitt, Patricia L. Blount, Peter S. Rabinovitch, Valerie W. Rusch, Brian J. Reid, An endoscopic biopsy protocol can differentiate high-grade dysplasia from early adenocarcinoma in Barrett's esophagus Gastroenterology. ,vol. 105, pp. 40- 50 ,(1993) , 10.1016/0016-5085(93)90008-Z
Nicholas J. Shaheen, Melissa A. Crosby, Eugene M. Bozymski, Robert S. Sandler, Is there publication bias in the reporting of cancer risk in Barrett's esophagus? Gastroenterology. ,vol. 119, pp. 333- 338 ,(2000) , 10.1053/GAST.2000.9302
Umakant Dave, Sami Shousha, David Westaby, Methylene blue staining: Is it really useful in Barrett's esophagus? Gastrointestinal Endoscopy. ,vol. 53, pp. 333- 335 ,(2001) , 10.1016/S0016-5107(01)70408-7
JR Olliver, CP Wild, P Sahay, S Dexter, LJ Hardie, Chromoendoscopy with methylene blue and associated DNA damage in Barrett's oesophagus The Lancet. ,vol. 362, pp. 373- 374 ,(2003) , 10.1016/S0140-6736(03)14026-3
Christian Ell, Andrea May, Liebwin Gossner, Oliver Pech, Erwin Günter, Gerd Mayer, Rolf Henrich, Michael Vieth, Hartmut Müller, Gerhard Seitz, Manfred Stolte, Endoscopic mucosal resection of early cancer and high-grade dysplasia in Barrett's esophagus Gastroenterology. ,vol. 118, pp. 670- 677 ,(2000) , 10.1016/S0016-5085(00)70136-3