Fatal levamisole toxicosis of captive kiwi (Apteryx mantelli)

作者: BD Gartrell , MR Alley , AH Mitchell

DOI: 10.1080/00480169.2005.36474

关键词:

摘要: Abstract CASE HISTORY: Nine of 24 captive kiwi treated with oral levamisole at a dose between 25–43 mg/kg showed signs respiratory distress. Six died within 4 h treatment and the remaining three made full recovery h. CLINICAL AND PATHOLOGICAL FINDINGS: Within 3–4 treatment, affected birds had an elevated rate, mucoid nasal discharge rapidly became comatose. Post mortem examination revealed accumulation thick mucus in cavity trachea. There was severe pulmonary congestion oedema early bronchopneumonia lungs five birds. In two birds, there acute hepatic degeneration necrosis one bird pancreatic necrosis. DIAGNOSIS: Acute toxicity. RELEVANCE: Kiwi were acutely sensitive to toxicity doses that are well safe range for domestic poultry. Levamisole should not be used as anthelmintic kiwi.

参考文章(12)
R. R. Dalvi, Pharmacology and toxicology of levamisole in domestic animals: a review. International Journal of Animal Sciences. ,vol. 5, pp. 15- 19 ,(1990)
W H Hsu, Toxicity and drug interactions of levamisole. Javma-journal of The American Veterinary Medical Association. ,vol. 176, pp. 1166- 1169 ,(1980)
IC Shaw, D Levon, F Jackson, R Turner, GD Cawley, Levamisole toxicity in fibre goats. Veterinary Record. ,vol. 133, pp. 627- 628 ,(1993) , 10.1136/VR.133.25-26.627
Geuke Gh, Nap Am, Slappendel Rj, Kooistra Hs, Ivermectin poisoning in a dog. The use of ivermectin in companion animals Tijdschrift Voor Diergeneeskunde. ,vol. 117, pp. 38- 40 ,(1992)
Donald W. Zantop, Greg J. Harrison, Branson W. Ritchie, Linda R. Harrison, Avian Medicine: Principles and Application ,(1994)
A. Vlassoff, P. B. McKenna, Nematode parasites of economic importance in sheep in New Zealand New Zealand Journal of Zoology. ,vol. 21, pp. 1- 8 ,(1994) , 10.1080/03014223.1994.9517971
Herbert Spencer, Pathology of the lung ,(1985)
Westerhof I, Ocular filariasis in a parakeet, a tropical surprise. Tijdschrift Voor Diergeneeskunde. ,(1992)
J. C. Haigh, Levamisole in waterfowl: trials on effect and toxicity The Journal of Zoo Animal Medicine. ,vol. 10, pp. 103- 105 ,(1979) , 10.2307/20094432
Phillip T. Robinson, Alexander G. Richter, A Preliminary Report on the Toxicity and Efficacy of Levamisole Phosphate in Zoo Birds The Journal of Zoo Animal Medicine. ,vol. 8, pp. 23- 26 ,(1977) , 10.2307/20460132