Fragrance compounds: The wolves in sheep’s clothings

摘要: In the past few decades, synthetic fragrance compounds have become ubiquitous components of personal care and household cleaning products. Overwhelming consumerism trends led to excess usage these chemicals. It has been observed that this fragrance-laden unhealthy lifestyle runs parallel with unprecedented rates diabetes, cancer, neural ailments, teratogenicity, transgender instances. The link between fragrances as multiplicity pathogens remained latent for decades. However, now health hazard its role in homeostasis breakdown is getting attention. adverse effects constituents phthalates, paraben, glutaraldehyde, hydroperoxides, oil turpentine, metals, nitro musks, essential oils, among others, are being identified. endocrine-immune-neural axis perturbation pathways chemicals proven. Despite revelations cause-effect nexus, a majority vulnerable populations unaware unmotivated avoid 'slow poisons'. Hence, researchers need further validate toxicity compounds, raise awareness towards risks. regard, number pathologies triggered by exposure, yet proven only scantily hypothesized. Analysis issues from multiple facets, including pivotal 'stressors - extracellular acidosis aromatase upregulation estrogen hyperproduction inflammation' proposed. Fragrance share configurational similarity carcinogenic environmental hydrocarbons they provoke expression cytochrome group monooxygenase enzyme aromatase. This aromatizes androgens form estrogen, powerful signaling hormone, which underlies morbidities. holistic review repertoire preliminary evidences robust hypotheses expected usher deserving extent research on pervasive risk.