Bronchoscopy and Lung Lavage Induced Bilateral Pulmonary Neutrophil Influx and Blood Leukocytosis in Dogs and Monkeys1–3

摘要: Investigators have previously determined that repetitive lung washes attract neutrophils to the lungs. They ascribed this attraction release of chemotactic factors. Our studies demonstrate lavage one lobe a attracts unwashed lobes as well; therefore, cannot be entirely due local agents. Further experiments showed influx also occurred after bronchoscopy without but not anesthesia alone. These suggest lungs mechanisms regulate and control neutrophil both locally contralaterally. It is yet clear whether controlling represent an integrated system in leukocyte traffic through In addition, cause increase blood count, with number young forms. Lung wash concentrates dramatic in...