Reductive Activation of Arenes: XIV. Effect of Medium on the Products Ratio in the Alkylation of Nitrobenzene Radical Anion Sodium Salt
作者： B. A. Selivanov , V. D. Shteingarts
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摘要: The product of nitrobenzene reduction by 1 equiv sodium reacted with tert-butyl iodide in liquid ammonia and its mixtures tetrahydrofuran hexamethylphosphoramide to afford a mixture compounds alkylated either the functional group (N-alkylation) or at benzene ring (C-alkylation). ratio N- C-alkylation products decreases solvents series NH3-THF (5.7) > NH3 (1.0) NH3-HMPA (0.6).
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