Generating mature lineages from induced pluripotent stem cells with mecp2 disruption
作者： Deepika Rajesh , Sarah Burton , Bradley Swanson , Christie Munn , Anne Strouse
DOI:
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摘要: Provided herein are methods for the efficient in vitro maintenance, expansion, culture, and/or differentiation of pluripotent cells with disruption MeCP2 gene into various erythroid, myeloid, lymphoid, or endoderm lineages, particularly mature erythrocytes. The may be maintained and differentiated under defined conditions; thus, use mouse feeder serum is not required certain embodiments precursor cells.
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