In vitro hydrolytic degradation of poly( para -dioxanone) with high molecular weight
作者： Wei Bai , Dongliang Chen , Qing Li , Hechun Chen , Shenglan Zhang
DOI: 10.1007/S10965-008-9250-Y
关键词:
摘要: The in vitro hydrolytic degradation of high molecular weight poly (para-dioxanone) was studied by examining the changes retention, water absorption, pH value, tensile strength, break elongation, thermal properties, and morphology PPDO phosphate buffered saline (PBS) (pH 7.44) at 37°C for 8 weeks. During degradation, all samples’ retention decreased absorption increased significantly, whereas hydrolysis rate bars varied with weight. Compared lower samples, higher samples exhibited rate. glass transition temperature (Tg) notably, while degrees crystallinity (Dc) increased. almost totally lost their strengths breaking elongation after 4 weeks degradation. results suggested that stability increase
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