25-Hydroxyvitamin D deficiency is associated with fatal stroke among whites but not blacks: The NHANES-III linked mortality files

摘要: Objective Deficient 25-hydroxyvitamin D (25[OH]D) levels are associated with cardiovascular disease (CVD) events and mortality. 25(OH)D deficiency stroke more prevalent in blacks. We examined whether low contributes to the excess risk of fatal blacks compared whites. Methods The Third National Health Nutrition Examination Survey, a probability sample U.S. civilians, measured CVD factors from 1988 through 1994. Vital status December 2006 was obtained by linkage Death Index. In white black adults without reported at baseline (n = 7981), Cox regression models were fit estimate hazard ratios (HR) for race. Results During median 14.1 y, there 116 60 strokes whites blacks, respectively. greater adjusted socioeconomic (HR 1.60, 95% confidence interval 1.01-2.53). Mean significantly lower (19.4 versus 30.8 ng/mL, respectively). multivariable-adjusted models, deficient than 15 ng/mL 2.13, 1.01-4.50) but not 0.93, 0.49-1.80). Conclusions Vitamin an increased death Although had higher rate whites, unrelated incidence. Therefore did explain this risk.