Pattern and multiple drug resistance of bacterial pathogens isolated from wound infection at University of Gondar Teaching Hospital, Northwest Ethiopia.

作者: Feleke Moges , Afework Kassu , Andargachew Mulu , Belay Tessema

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摘要: Objectives Antibiotics resistance among bacteria is a worldwide problem. The situation in developing countries like Ethiopia particularly serious. Since the presence of drug resistant environment are threat for public health, up-to-date information on local pathogens and sensitivity pattern very crucial to treat patients. aim this study assess bacterial from wound infection their susceptibility common antibiotics. Materials methods This laboratory based retrospective 151 swabs tests was conducted Bacteriology Laboratory University Gondar Teaching Hospital. samples were collected processed following standard microbiological techniques as part routine clinical management patient. Antibiotic testing done pure culture isolates employing disc-diffusion method commonly used Results Bacterial isolated 79 patients showing an isolation rate 52%. Staphylococcus aureus predominant species 65% (51/79) followed by Escherichia coli, 8/79 (10%), Klebsiella pneumoniae 9% (7/79), Proteus 4% (3/79) Streptococci (3/7). Among Gram-positive bacteria, S. showed high level against penicillin 59% (30/51), tetracycline 57% (29/51), ampicillin 55% (28/51) co-trimoxazole 35% (18/51). E. coli found be 87% (7/8), also (7/8) 63% (5/8). over all multiple patterns 78.5%. Conclusions frequency single well alarmingly high. might reflection inappropriate use antimicrobials, lack diagnostic services or unavailability guideline regarding selection drugs. Thus, rational drugs should practiced.

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