Endocrine Therapy for Hormone Receptor–Positive Metastatic Breast Cancer: American Society of Clinical Oncology Guideline

摘要: PurposeTo develop recommendations about endocrine therapy for women with hormone receptor (HR) –positive metastatic breast cancer (MBC).MethodsThe American Society of Clinical Oncology convened an Expert Panel to conduct a systematic review evidence from 2008 through 2015 create informed by that evidence. Outcomes interest included sequencing hormonal agents, agents compared chemotherapy, targeted biologic therapy, and treatment premenopausal women. This guideline puts forth as HR-positive MBC.RecommendationsSequential is the preferential most MBC. Except in cases immediately life-threatening disease, alone or combination, should be used initial treatment. Patients whose tumors express any level receptors offered therapy. Treatment based on type adjuvant treatment,...