A new class of mutants with an elevated basal level of the galactose enzymes in E. coli
作者： Brigitte Rosenwirth
DOI: 10.1007/BF00271652
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摘要: A new type of mutation is described which affects the regulation gal-operon, and maps distant from structural genes galR-gene. The mutants were found among survivors a heat induction thermosensitive prophage λc I857 . Their basal enzyme level 2–3 times higher than wild-type level. They carry deletions covering region attλ to chlA. deletion exerts its influence in position trans, effect can be complemented. presence does not affect lac-operon.
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sci-hub.se 参考文章(28)
H. Saedler, A. Gullon, L. Fiethen, P. Starlinger, Negative control of the galactose operon in E. coli. Molecular Genetics and Genomics. ,vol. 102, pp. 79- 88 ,(1968) , 10.1007/BF00341872
K. A. Stacey, Eva Simson, Improved Method for the Isolation of Thymine-Requiring Mutants of Escherichia coli Journal of Bacteriology. ,vol. 90, pp. 554- 555 ,(1965) , 10.1128/JB.90.2.554-555.1965
G. Buttin, Mécanismes régulateurs dans la biosynthèse des enzymes du métabolisme du galactose chez Escherichia coli K12 Journal of Molecular Biology. ,vol. 7, pp. 183- IN2 ,(1963) , 10.1016/S0022-2836(63)80045-5
R. Thomas, Control of development in temperate bacteriophages Journal of Molecular Biology. ,vol. 22, pp. 79- 95 ,(1966) , 10.1016/0022-2836(66)90181-1
S. R. Kupor, D. G. Fraenkel, 6-Phosphogluconolactonase Mutants of Escherichia coli and a Maltose Blue Gene Journal of Bacteriology. ,vol. 100, pp. 1296- 1301 ,(1969) , 10.1128/JB.100.3.1296-1301.1969
A. Lewis Farr, Oliver H. Lowry, Rose J. Randall, Nira J. Rosebrough, Protein Measurement with the Folin Phenol Reagent Journal of Biological Chemistry. ,vol. 193, pp. 265- 275 ,(1951)
James A Shapiro, Sankar L Adhya, The galactose operon of E. coli K-12. II. A deletion analysis of operon structure and polarity. Genetics. ,vol. 62, pp. 249- 264 ,(1969) , 10.1093/GENETICS/62.2.249
Masahide Ishibashi, Yoshinobu Sugino, Yukinori Hirota, CHROMOSOMAL LOCATION OF THYMINE AND ARGININE GENES IN ESCHERICHIA COLI AND AN F′ INCORPORATING THEM Journal of Bacteriology. ,vol. 87, pp. 554- 561 ,(1964) , 10.1128/JB.87.3.554-561.1964
John R. Sherman, Julius Adler, Galactokinase from Escherichia coli Journal of Biological Chemistry. ,vol. 238, pp. 873- 878 ,(1963) , 10.1016/S0021-9258(18)81229-7
Leo Fiethen, Peter Starlinger, Mutations in the galactose-operator Molecular Genetics and Genomics. ,vol. 108, pp. 322- 330 ,(1970) , 10.1007/BF00267769