Pancreas-derived plasminogen activator inhibitor

作者: Reiner L. Gentz , Steven M. Ruben , Y. Eric Shi , Jian Ni

DOI:

关键词:

摘要: The present invention relates to a novel member of the plasminogen activator inhibitor protein family. In particular, isolated nucleic acid molecules are provided encoding pancreas-derived protein. Pancreas-derived polypeptides also as vectors, host cells and recombinant methods for producing same. further treating physiologic pathologic disease conditions, including breast cancer, diagnostic detecting disorders.

参考文章(19)
Barry Robson, Jean Garnier, Introduction to proteins and protein engineering ,(1986)
J. Thomas Ngo, Joe Marks, Martin Karplus, Computational Complexity, Protein Structure Prediction, and the Levinthal Paradox The Protein Folding Problem and Tertiary Structure Prediction. pp. 433- 506 ,(1994) , 10.1007/978-1-4684-6831-1_14
Craig G. Wilde, Scott Michael Braxton, Dinh Diep, Pancreas-derived serpin ,(1996)
Tetsumei URANO, Leif STRANDBERG, Lennart B.-A. JOHANSSON, Tor NY, A substrate-like form of plasminogen-activator-inhibitor type 1. Conversions between different forms by sodium dodecyl sulphate. FEBS Journal. ,vol. 209, pp. 985- 992 ,(1992) , 10.1111/J.1432-1033.1992.TB17372.X
R.W. Carrell, P.A. Pemberton, D.R. Boswell, The Serpins: Evolution and Adaptation in a Family of Protease Inhibitors Cold Spring Harbor Symposia on Quantitative Biology. ,vol. 52, pp. 527- 535 ,(1987) , 10.1101/SQB.1987.052.01.060