Strain-Encoded Cardiac Magnetic Resonance During High-Dose Dobutamine Stress Testing for the Estimation of Cardiac Outcomes: Comparison to Clinical Parameters and Conventional Wall Motion Readings

作者: Grigorios Korosoglou , Gitsios Gitsioudis , Andreas Voss , Stephanie Lehrke , Nina Riedle

DOI: 10.1016/J.JACC.2011.03.063

关键词:

摘要: Objectives The purpose of this study was to determine the prognostic value strain-encoded magnetic resonance imaging (SENC) during high-dose dobutamine stress cardiac (DS-MRI) compared with conventional wall motion readings. Background Detection inducible ischemia by DS-MRI on basis assessing cine images is subjective and depends experience readers, which may influence not only diagnostic classification but also risk stratification patients ischemic heart disease. Methods In all, 320 consecutive suspected or known coronary artery disease underwent DS-MRI, using a standard protocol in 1.5T MR scanner. Wall abnormalities (WMA) myocardial strain were assessed at baseline stress, outcome data including deaths, nonfatal infarctions (“hard events”), revascularization procedures performed >90 days after scans collected. Results Thirty-five hard events occurred 28 ± 9 month follow-up period, 10 deaths 25 infarctions, 32 revascularization. Using series Cox proportional-hazards models, both resting WMA offered incremental information for assessment clinical variables (chi-square = 13.0 vs. chi-square 26.1 adding WMA, p Conclusions Strain-encoded MRI aids accurate identification high future procedures, beyond atherogenic factors images. (Strain-Encoded Cardiac Magnetic Resonance Imaging as an Adjunct Dobutamine Stress Testing; NCT00758654 )

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