TGFB1 and TGFBR2 functional polymorphisms and risk of esophageal squamous cell carcinoma: a case–control analysis in a Chinese population
作者： Guangfu Jin , Yimei Deng , Ruifen Miao , Zhibin Hu , Yan Zhou
DOI: 10.1007/S00432-007-0290-1
关键词:
摘要: Purpose Transforming growth factor β1 (TGF-β1) and its receptor II (TGF-βRII) are two key components of TGF-β signaling play an important role in carcinogenesis. Several functional polymorphisms were identified TGFB1 TGFBR2 associated with elevated serum or plasma level TGF-β1 enhanced transcription activity TGFBR2. This population-based case–control study was to evaluate the contribution C-509T, Leu10Pro G-875A risk esophageal squamous cell carcinoma (ESCC).
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Rik Derynck, Rosemary J. Akhurst, Allan Balmain, TGF-beta signaling in tumor suppression and cancer progression. Nature Genetics. ,vol. 29, pp. 117- 129 ,(2001) , 10.1038/NG1001-117
Yoon Jun Kim, Hyo-Suk Lee, Jong Pil Im, Byung-Hoon Min, Hyun Dae Kim, Ji Bong Jeong, Jung-Hwan Yoon, Chung Yong Kim, Myung Soo Kim, Jun Yeon Kim, Ji Hyun Jung, Lyoung Hyo Kim, Byung Lae Park, Hyoung Doo Shin, Association of transforming growth factor-β1 gene polymorphisms with a hepatocellular carcinoma risk in patients with chronic hepatitis B virus infection Experimental and Molecular Medicine. ,vol. 35, pp. 196- 202 ,(2003) , 10.1038/EMM.2003.27
Mitsuhiro Yokota, Sahoko Ichihara, Tong-Lang Lin, Nobuo Nakashima, Yoshiji Yamada, Association of a T29→C Polymorphism of the Transforming Growth Factor-β1 Gene With Genetic Susceptibility to Myocardial Infarction in Japanese Circulation. ,vol. 101, pp. 2783- 2787 ,(2000) , 10.1161/01.CIR.101.24.2783
Erin K. Luedecking, Steven T. DeKosky, Haider Mehdi, Mary Ganguli, M. Ilyas Kamboh, Analysis of genetic polymorphisms in the transforming growth factor-β1 gene and the risk of Alzheimer's disease Human Genetics. ,vol. 106, pp. 565- 569 ,(2000) , 10.1007/S004390000313
Guangfu Jin, Lina Wang, Wensen Chen, Zhibin Hu, Yan Zhou, Yongfei Tan, Jianming Wang, Zhaolai Hua, Weiliang Ding, Jing Shen, Zuofeng Zhang, Xinru Wang, Yaochu Xu, Hongbing Shen, Variant alleles of TGFB1 and TGFBR2 are associated with a decreased risk of gastric cancer in a Chinese population International Journal of Cancer. ,vol. 120, pp. 1330- 1335 ,(2007) , 10.1002/IJC.22443
Edward R Seijo, Huijuan Song, Melanie A Lynch, Ron Jennings, Xing Qong, Emmanuel Lazaridis, Carlos Muro-Cacho, Christopher M Weghorst, Teresita Muñoz-Antonia, Identification of genetic alterations in the TGFβ type II receptor gene promoter Mutation Research. ,vol. 483, pp. 19- 26 ,(2001) , 10.1016/S0027-5107(01)00217-2
Lina Wang, Wensen Chen, Jianmin Wang, Yongfei Tan, Yan Zhou, Weiliang Ding, Zhaolai Hua, Jing Shen, Yaochu Xu, Hongbing Shen, Reduced folate carrier gene G80A polymorphism is associated with an increased risk of gastroesophageal cancers in a chinese population European Journal of Cancer. ,vol. 42, pp. 3206- 3211 ,(2006) , 10.1016/J.EJCA.2006.04.022
Aesun Shin, Xiao-Ou Shu, Qiuyin Cai, Yu-Tang Gao, Wei Zheng, Genetic Polymorphisms of the Transforming Growth Factor-β1 Gene and Breast Cancer Risk: A Possible Dual Role at Different Cancer Stages Cancer Epidemiology, Biomarkers & Prevention. ,vol. 14, pp. 1567- 1570 ,(2005) , 10.1158/1055-9965.EPI-05-0078
Joan Massagué, Stacy W Blain, Roger S Lo, TGFBETA SIGNALING IN GROWTH CONTROL, CANCER, AND HERITABLE DISORDERS Cell. ,vol. 103, pp. 295- 309 ,(2000) , 10.1016/S0092-8674(00)00121-5
Rosemary J Akhurst, Rik Derynck, TGF-β signaling in cancer – a double-edged sword Trends in Cell Biology. ,vol. 11, ,(2001) , 10.1016/S0962-8924(01)02130-4