Detection and characterization of circulating and disseminated prostate cancer cells

摘要: Abstract The dissemination of prostate cancer cells to secondary sites appears be an intermediate step in the formation tumor metastases. However, significance cell into blood and bone marrow as well characteristics these remains largely unknown. In attempts correlate presence disseminated with disease prognosis, studies have utilized a range molecular histologic techniques. results this research been inconclusive terms clinical utility. Nevertheless, they demonstrated that are detectable present much more often than would expected based on rate recurrence. Further has thus begun focus isolation individual which can then analyzed techniques such gene expression microarrays comparative genomic hybridization order better characterize cells. This review paper will examine various methods detecting patients correlating variables. Additionally, we discuss analysis their potential value helping understand relationship between metastasis.