An acoustic plate mode biosensor
作者： J.C. Andle , J.F. Vetelino , M.W. Lade , D.J. McAllister
DOI: 10.1016/0925-4005(92)80180-6
关键词:
摘要: A prototype biosensor, which utilizes an acoustic plate mode (APM) in a piezoelectric crystal as the sensing element, has been designed, fabricated and tested. The APM is selectively excited received by aluminum interdigital transducers (IDTs), are on Z-cut X-propagating lithium niobate (ZX-LiNbO3) substrate using standard photolithographic techniques. biological film bound to face of ZX-LiNbO3 opposite IDTs. Appropriate r.f. electronics used with device form complete biosensor. Tests relating detection deoxyribonucleic acid (DNA) hybridization demonstrate that biosensor exhibits high level sensitivity, selectivity reproducibility.
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sci-hub.se 参考文章(21)
J. Andle, J. Vetelino, M. Lade, D. McAllister, Detection of nucleic acid hybridization with an acoustic plate mode microsensor IEEE Symposium on Ultrasonics. pp. 291- 294 ,(1990) , 10.1109/ULTSYM.1990.171370
Gary S Calabrese, Hank Wohltjen, Manas K Roy, None, Surface acoustic wave devices as chemical sensors in liquids. Evidence disputing the importance of Rayleigh wave propagation Analytical Chemistry. ,vol. 59, pp. 833- 837 ,(1987) , 10.1021/AC00133A010
Suresh K. Bhatia, Lisa C. Shriver-Lake, Kimberly J. Prior, Jacque H. Georger, Jeffrey M. Calvert, Reinhard Bredehorst, Frances S. Ligler, Use of thiol-terminal silanes and heterobifunctional crosslinkers for immobilization of antibodies on silica surfaces. Analytical Biochemistry. ,vol. 178, pp. 408- 413 ,(1989) , 10.1016/0003-2697(89)90662-3
T. Nomura, M. Okuhara, Frequency shifts of piezoelectric quartz crystals immersed in organic liquids Analytica Chimica Acta. ,vol. 142, pp. 281- 284 ,(1982) , 10.1016/S0003-2670(01)95290-0
A. J. Ricco, S. J. Martin, Acoustic wave viscosity sensor Applied Physics Letters. ,vol. 50, pp. 1474- 1476 ,(1987) , 10.1063/1.97804
Harold E. Hager, Peter D. Verge, Multicomponent gas analysis via transient operation of liquid coated piezoelectric crystal detectors Sensors and Actuators. ,vol. 7, pp. 271- 283 ,(1985) , 10.1016/0250-6874(85)80007-X
K Keiji Kanazawa, Joseph G Gordon, The oscillation frequency of a quartz resonator in contact with liquid Analytica Chimica Acta. ,vol. 175, pp. 99- 105 ,(1985) , 10.1016/S0003-2670(00)82721-X
Anthony P.F. Turner, Current trends in biosensor research and development Sensors and Actuators. ,vol. 17, pp. 433- 450 ,(1989) , 10.1016/0250-6874(89)80030-7
Joy E. Roederer, Glenn J. Bastiaans, Microgravimetric immunoassay with piezoelectric crystals Analytical Chemistry. ,vol. 55, pp. 2333- 2336 ,(1983) , 10.1021/AC00264A030
Hiroshi. Muramatsu, Jonathan M. Dicks, Eiichi. Tamiya, Isao. Karube, Piezoelectric crystal biosensor modified with protein A for determination of immunoglobulins. Analytical Chemistry. ,vol. 59, pp. 2760- 2763 ,(1987) , 10.1021/AC00150A007