Association between Kidney Function and Framingham Global Cardiovascular Disease Risk Score: A Chinese Longitudinal Study

摘要: Background Chronic kidney disease (CKD) is generally considered an independent risk factor for cardiovascular (CVD) development, but rates in individuals with estimated glomerular filtration rate (eGFR) >60 ml/min/1.73 m2 are uncertain. The Framingham global CVD score (FRS) equation a widely accepted tool used to predict the general population. purpose of present study was examine whether association exists between eGFR and FRS Chinese population no CKD or CVD. Methods A total 333 participants were divided into three groups based on FRS. Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) CKD-EPI Asians (CKD-EPI-ASIA) measure eGFR. Results significant inverse confirmed Pearson correlation coefficients –0.669, –0.698 (eGFRCKD-EPI, P 0.05; similar results according CKD-EPI-ASIA equation). In low- moderate-risk new-groups, this became stronger increased (eGFRCKD-EPI-ASIA, r = –0557, –0.622 –0.326, –0.329, P<0.01). contrast from 2008, independently associated following adjustment traditional factors (P<0.05). Conclusion Renal function has multiple influences predicting various populations. With increasing decreasing eGFR, it also CVD, even m2.