The Risk for Incident Ischemic Heart Disease According to Estimated Glomerular Filtration Rate in A Korean Population

摘要: Aim Chronic kidney disease, evaluated by the estimated glomerular filtration rate (eGFR), is an established risk factor for cardiovascular disease. However, association between renal function stratified eGFR and of incident ischemic heart disease (IHD) in a community-based Asian population still inconclusive. Study design Retrospective longitudinal observational study. Method In data from 206,919 Korean patients registered National Health Insurance Corporation (NHIC), we analyzed IHD according to quartiles (Q) (ml/min/1.73 m2) (Q1 ＜71.07, Q2: 71.07-83.16, Q3: 83.17-95.49, Q4 ＞95.50). The identification was based on International Classification Diseases (ICD) (ICD code: I20-I25) NHIC. Cox proportional hazards model used calculate adjusted hazard ratios (HRs) 95% confidence intervals (CI) quartile groups levels. Results Q1 had more unfavorable baseline metabolic conditions than other groups. Considering as reference, unadjusted HRs (95% CIs) increased significantly order Q3 (1.42 [1.29-1.56]), Q2 (1.51 [1.38-1.67]), (2.11 [1.93-2.30]), fully (1.15 [1.04-1.27]) (1.31 [1.18-1.44]). Conclusion individuals with ≤ 83.16. Mildly decreased potential IHD.