Antibiotics, microbiota, and immune defense.

作者: Carles Ubeda , Eric G. Pamer

DOI: 10.1016/J.IT.2012.05.003

关键词:

摘要: The gastrointestinal tract microbiota contributes to the development and differentiation of mammalian immune system. composition affects responses susceptibility infection by intestinal pathogens allergic inflammatory bowel diseases. Antibiotic administration, while facilitating clearance targeted infections, also perturbs commensal microbial communities decreases host resistance antibiotic-resistant microbes. Here, we review recent advances that begin define interactions between complex populations system how this relation is perturbed antibiotic administration. We further discuss antibiotic-induced disruption homeostasis can lead disease strategies restore defenses during

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