Electrophysiological Study of the Neostriatum in Brain Slice Preparation

摘要: The neostriatum of mammalian species consists the caudate and putaman is a major component basal ganglia (Carpenter, 1981). It relatively large nuclear mass easily dissected from rest brain. In slice preparation, severed extrinsic connections. Neuronal responses recorded following electrical stimulation in preparation therefore reflect only activities those neuronal elements left intact. These would include soma, dendrites, and, so long as their course remains within slice, axons neostriatal neurons. Added to these are fibers origin terminals, isolated cell bodies, but remaining electrically excitable. be well suited study local interactions among striatal action monosynaptic afferents. enables investigator manipulate extracellular milieu controlled manner. For this reason, it also for studying putative neurotransmitters other agents on neurons characterizing relationships between membrane specific electrolytes.