Immunological and chemotherapeutic prevention and control of oncogenic viruses.

作者: Michael A. Chirigos , Takis S. Papas

DOI: 10.1016/S1054-3589(08)60220-3

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摘要: Publisher Summary This chapter discusses the immunological and chemotherapeutic prevention control of oncogenic viruses. The development in vitro (tissue culture) assay systems has facilitated rapid testing drugs other potentially active antiviral agents. In addition, these assays have been found useful studies designed to elucidate mechanism inhibitory action Murine leukemia viruses are assayed by XC-test, which a quantitative number syncytia formed. Infective titers murine sarcoma virus can be quantitated foci formed on mouse embryo fibroblast cultures. These shown for isolating naturally occurring leukemic group tissue culture determining helper role that possess defective virus. Several virus-transformed cell lines established employed drugs. An alkaloid extract Narcissus bulb rifampycin derivatives exert an effect replication.

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